Regulation of the mitochondrial proton gradient by cytosolic Ca2+ signals

@article{Poburko2012RegulationOT,
  title={Regulation of the mitochondrial proton gradient by cytosolic Ca2+ signals},
  author={Damon Poburko and Nicolas Demaurex},
  journal={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={2012},
  volume={464},
  pages={19-26}
}
Mitochondria convert the energy stored in carbohydrate and fat into ATP molecules that power enzymatic reactions within cells, and this process influences cellular calcium signals in several ways. By providing ATP to calcium pumps at the plasma and intracellular membranes, mitochondria power the calcium gradients that drive the release of Ca2+ from stores and the entry of Ca2+ across plasma membrane channels. By taking up and subsequently releasing calcium ions, mitochondria determine the… Expand
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