Regulation of the mRNA levels of nimA, a gene required for the G2-M transition in Aspergillus nidulans

  title={Regulation of the mRNA levels of nimA, a gene required for the G2-M transition in Aspergillus nidulans},
  author={Stephen A Osmani and Gregory S. May and N. Ronald Morris},
  journal={The Journal of Cell Biology},
  pages={1495 - 1504}
The temperature-sensitive cell cycle mutation nimA5 causes nuclei of Aspergillus nidulans to be blocked in late G2 at restrictive temperature. Under these conditions the spindle pole body divides but does not separate and the mitotic index drops to zero. If nimA5 is blocked for more than one doubling time and then shifted from restrictive to permissive temperature, nuclei immediately enter mitosis, the mitotic spindle forms, and the chromosomes condense (Oakley, B. R., and N. R. Morris, 1983, J… CONTINUE READING


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