Regulation of the immune system by the resident intestinal bacteria.

  title={Regulation of the immune system by the resident intestinal bacteria.},
  author={Nobuhiko Kamada and Gabriel N{\'u}{\~n}ez},
  volume={146 6},
The microbiota is an important factor in the development of the immune response. The interaction between the gastrointestinal tract and resident microbiota is well balanced in healthy individuals, but its breakdown can lead to intestinal and extraintestinal disease. We review current knowledge about the mechanisms that regulate the interaction between the immune system and the microbiota, focusing on the role of resident intestinal bacteria in the development of immune responses. We also… CONTINUE READING
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