Regulation of the feedback antagonist naked cuticle by Wingless signaling.

@article{Chang2008RegulationOT,
  title={Regulation of the feedback antagonist naked cuticle by Wingless signaling.},
  author={Jinhee L Chang and Mikyung V. Chang and Scott Barolo and Ken M Cadigan},
  journal={Developmental biology},
  year={2008},
  volume={321 2},
  pages={
          446-54
        }
}
Signaling pathways usually activate transcriptional targets in a cell type-specific manner. Notable exceptions are pathway-specific feedback antagonists, which serve to restrict the range or duration of the signal. These factors are often activated by their respective pathways in a broad array of cell types. For example, the Wnt ligand Wingless (Wg) activates the naked cuticle (nkd) gene in all tissues examined throughout Drosophila development. How does the nkd gene respond in such an… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 19 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

CBP/p300 are bimodal regulators of Wnt signaling.

VIEW 7 EXCERPTS

A 3' cis-regulatory region controls wingless expression in the Drosophila eye and leg primordia.

VIEW 1 EXCERPT