Regulation of the expression of zinc finger protein genes by microRNAs enriched within acute lymphoblastic leukemia-derived microvesicles.

@article{Lu2015RegulationOT,
  title={Regulation of the expression of zinc finger protein genes by microRNAs enriched within acute lymphoblastic leukemia-derived microvesicles.},
  author={Lixia Lu and Xiangjun Chen and Huimin Tao and Wenqian Xiong and Shenghua Jie and Huiyu Li},
  journal={Genetics and molecular research : GMR},
  year={2015},
  volume={14 4},
  pages={11884-95}
}
Microvesicles (MVs) are submicrometric membrane fragments that can "engulf" cytoplasmic contents such as microRNAs (miRNAs) from their cellular origin. The study of miRNAs carried within MVs might provide insights into the roles that miRNAs play in the underlying pathophysiologic processes of acute lymphoblastic leu-kemia (ALL). We identified numerous dysregulated MV miRNAs in patients with B- and T-cell ALL by using Agilent microarray analysis. Selected miRNAs obtained by microarray profiling… CONTINUE READING
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