Regulation of the expression of autoimmunity in NZB x NZW F1 mice by sex hormones.

@article{Melez1978RegulationOT,
  title={Regulation of the expression of autoimmunity in NZB x NZW F1 mice by sex hormones.},
  author={Kathleen A. Melez and John P. Reeves and Alfred D. Steinberg},
  journal={Journal of immunopharmacology},
  year={1978},
  volume={1 1},
  pages={27-42}
}
This study examines the role of sex hormones in modulating the expression of autoimmunity in NZB x NZW F1 mice. Male sex hormones were found to retard disease. Differences were noted between prepubertally and postpubertally altered males and females. The presence of male sex hormones prepubertally was associated with marked retardation of the development of… CONTINUE READING