Regulation of the expression of Th17 cells and regulatory T cells by IL-27 in patients with unexplained early recurrent miscarriage.

@article{Wang2013RegulationOT,
  title={Regulation of the expression of Th17 cells and regulatory T cells by IL-27 in patients with unexplained early recurrent miscarriage.},
  author={Wen-juan Wang and Fujun Liu and Hong-mei Qu and Cui-fang Hao and Qing-Lan Qu and Xiong-Wang and Hong-chu Bao and Xin-rong Wang},
  journal={Journal of reproductive immunology},
  year={2013},
  volume={99 1-2},
  pages={39-45}
}
In normal pregnancy, tolerance of the maternal immune system with regard to the genetically incompatible fetus depends on the interactions of an array of cytokines secreted by maternal and fetal cells at the site of implantation. Earlier research indicating that altered immunity exists in unexplained recurrent miscarriage (RM) has been dominated by the Th1/Th2 hypothesis. Recently, the Th1/Th2 paradigm has been expanded into the Th1/Th2/Th17 and regulatory T cells paradigm. We recently… CONTINUE READING
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