Regulation of the double-stranded RNA-dependent protein kinase PKR by RNAs encoded by a repeated sequence in the Epstein-Barr virus genome.

Abstract

During the initial infection of B lymphocytes by Epstein-Barr virus (EBV) only a few viral genes are expressed, six of which encode the EBV nuclear antigens, EBNAs 1-6. The majority of EBNA mRNAs share common 5'-ends containing a variable number of two alternating and repeated exons transcribed from the BamHI W major internal repeats of the viral DNA. These… (More)

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@article{Elia1996RegulationOT, title={Regulation of the double-stranded RNA-dependent protein kinase PKR by RNAs encoded by a repeated sequence in the Epstein-Barr virus genome.}, author={Andrew E. H. Elia and Kirsty Laing and Andrew Schofield and Vivienne J. Tilleray and Michelle Clemens}, journal={Nucleic acids research}, year={1996}, volume={24 22}, pages={4471-8} }