Regulation of the cystic fibrosis transmembrane conductance regulator channel by beta-adrenergic agonists and vasoactive intestinal peptide in rat smooth muscle cells and its role in vasorelaxation.

@article{Robert2004RegulationOT,
  title={Regulation of the cystic fibrosis transmembrane conductance regulator channel by beta-adrenergic agonists and vasoactive intestinal peptide in rat smooth muscle cells and its role in vasorelaxation.},
  author={Renaud Robert and Vincent Thoreau and Caroline Norez and A. Cantereau and Alain Kitzis and Yvette Mettey and Christian Rogier and Fr{\'e}d{\'e}ric Becq},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 20},
  pages={21160-8}
}
The signaling events that regulate vascular tone include voltage-dependent Ca(2+) influx and the activities of various ionic channels; which molecular entities are involved and their role are still a matter of debate. Here we show expression of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel in rat aortic smooth muscle cells. Immunoprecipitation and in vitro protein kinase A phosphorylation show the appearance of mature band C of CFTR. An immunohistochemistry study… CONTINUE READING
17 Citations
1 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.

Expression of CFTR in Smooth Muscle

  • S. Sorota
  • March 11,
  • 1999

Similar Papers

Loading similar papers…