Regulation of the Porphyromonas gingivalis fimA (Fimbrillin) gene.

  title={Regulation of the Porphyromonas gingivalis fimA (Fimbrillin) gene.},
  author={Hua Xie and Whasun Oh Chung and Yoonsuk Park and Richard J Lamont},
  journal={Infection and immunity},
  volume={68 12},
In common with many bacterial virulence genes, the fimbrillin (fimA) gene of Porphyromonas gingivalis is modulated in response to environmental fluctuation. The trans-acting components that comprise the regulatory system for transcriptional activity of the fimA gene in P. gingivalis were investigated. Three major proteins were found to bind to the upstream region of the fimA promoter. One of these proteins was fimbrillin itself, and the other two were a major arginine protease (Rgp) and lysine… CONTINUE READING

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