Regulation of the Pathological Vasculature of Malignant Astrocytomas by Angiopoietin-11

Malignant astrocytomas are the most common and highly vascularized of all primary adult brain tumors. The histopathological hallmarks of malignant astrocytomas are microvascular proliferation and formation of vascular entities, which are referred to as ‘‘glomeruloid bodies.’’ The significance of glomeruloid bodies and the molecular mechanisms driving the… CONTINUE READING