Regulation of the Na(+), glucose cotransporter by PIKfyve and the serum and glucocorticoid inducible kinase SGK1.

@article{Shojaiefard2007RegulationOT,
  title={Regulation of the Na(+), glucose cotransporter by PIKfyve and the serum and glucocorticoid inducible kinase SGK1.},
  author={Manzar Shojaiefard and Nathalie Strutz-Seebohm and Jeremy Tavare and Guiscard Seebohm and Florian Lang},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={359 4},
  pages={843-7}
}
The Na(+), glucose cotransporter SGLT1 (SLC5A1) accomplishes Na(+)-dependent concentrative cellular glucose uptake. SGLT1 activity is enhanced by the serum and glucocorticoid inducible kinase SGK1. As shown recently, the stimulating effect of protein kinase B on the glucose carrier GLUT4 involves the mammalian phosphatidylinositol-3-phosphate-5-kinase… CONTINUE READING