Regulation of the Hippo Pathway Transcription Factor TEAD.

  title={Regulation of the Hippo Pathway Transcription Factor TEAD.},
  author={Kimberly C. Lin and Hyun Woo Park and Kun Liang Guan},
  journal={Trends in biochemical sciences},
  volume={42 11},
The TEAD transcription factor family is best known for transcriptional output of the Hippo signaling pathway and has been implicated in processes such as development, cell growth and proliferation, tissue homeostasis, and regeneration. Our understanding of the functional importance of TEADs has increased dramatically since its initial discovery three decades ago. The majority of our knowledge of TEADs is in the context of Hippo signaling as nuclear DNA-binding proteins passively activated by… CONTINUE READING
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