Regulation of the Escherichia coli sigma-dependent envelope stress response.

  title={Regulation of the Escherichia coli sigma-dependent envelope stress response.},
  author={Benjamin M. Alba and Carol A. Gross},
  journal={Molecular microbiology},
  volume={52 3},
The Escherichia colisigma(E)-dependent stress response pathway controls the expression of genes encoding periplasmic folding catalysts, proteases, biosynthesis enzymes for lipid A (a component of lipopolysaccharide or LPS) and other proteins known or predicted to function in or produce components of the envelope. When E. coli is subjected to heat or other stresses that generate unfolded envelope proteins, sigma(E) activity is induced. Four key players in this signal transduction pathway have… CONTINUE READING
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