Regulation of the CD8+ T cell responses against Plasmodium liver stages in mice.

Abstract

CD8+ T cells induced by immunization with Plasmodium sporozoites play a major role in protective immunity against parasite infection, inhibiting the development of liver stages. The activation of these T cells is initiated just a few hours after exposure to parasites and progresses rapidly through a tightly regulated program. Effector functions in CD8+ T… (More)

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