Regulation of testicular human chorionic gonadotrophin binding in prolactin-deficient Snell dwarf mice.

The regulation of binding of 125 I-labelled human chorionic gonadotrophin (hCG) to testis was studied in mutant mice with congenital deficiency of prolactin (dw/dw), in mice with prolactin deficiency induced by treatment with bromocriptine and in normal untreated mice. After injection of hCG, normal mice showed a dose-related decrease in testicular hCG… CONTINUE READING