Regulation of terminal differentiation of cultured human keratinocytes by vitamin A

@article{Fuchs1981RegulationOT,
  title={Regulation of terminal differentiation of cultured human keratinocytes by vitamin A},
  author={E. Fuchs and H. Green},
  journal={Cell},
  year={1981},
  volume={25},
  pages={617-625}
}
Vitamin A is known to exert an important influence on epithelial differentiation. The fetal calf serum supplement of cell-culture medium contains enough of the vitamin to affect the differentiation of cultured keratinocytes derived from epidermis and from other stratified squamous epithelia. The cellular and molecular properties of the cultures are altered when the medium is supplemented with serum from which the vitamin A has been removed by solvent extraction (delipidized serum). Cell… Expand
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