Regulation of synovial cell apoptosis by proteasome inhibitor.

Abstract

OBJECTIVE Recent studies have shown the importance of proteasome function in the regulation of apoptosis. This study examined whether inhibition of proteasome function mediates apoptosis of synovial cells, and whether cytokines modulate this process. METHODS Type B synovial cells (fibroblast-like synovial cells) were cultured with tumor necrosis factor… (More)

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@article{Kawakami1999RegulationOS, title={Regulation of synovial cell apoptosis by proteasome inhibitor.}, author={Atsushi Kawakami and Toshihiro Nakashima and Hiroki Sakai and Ayumi Hida and Shiro M Urayama and Shinji Yamasaki and H. Nakamura and Hiroyuki Ida and Yukito Ichinose and Tetsuji Aoyagi and Itaru Furuichi and Mihoko N. Nakashima and Kiyoshi Migita and Yoshiki Kawabe and Katsumi Eguchi}, journal={Arthritis and rheumatism}, year={1999}, volume={42 11}, pages={2440-8} }