Regulation of swelling-activated chloride channels in embryonic chick heart cells

Abstract

ABSTRACTSwelling-activated Cl− currents, I(Cl,swell), were measured during hyposmotic shock in white Leghorn embryonic chick heart cells using the whole-cell recording of patch-clamp technique. Genistein, an inhibitor of protein tyrosine kinase (PTK), suppressed I(Cl,swell). Under isosmotic condition phorbol 12-myristate 13-acetate (PMA), an activator of… (More)
DOI: 10.1038/sj.cr.7290147

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