Regulation of stilbene biosynthesis in plants

@article{Dubrovina2017RegulationOS,
  title={Regulation of stilbene biosynthesis in plants},
  author={Alexandra S. Dubrovina and Konstantin V Kiselev},
  journal={Planta},
  year={2017},
  volume={246},
  pages={597-623}
}
AbstractMain conclusionThis review analyzes the advances in understanding the natural signaling pathways and environmental factors regulating stilbene biosynthesis. We also discuss the studies reporting on stilbene content and repertoire in plants. Stilbenes, including the most-studied stilbene resveratrol, are a family of phenolic plant secondary metabolites that have been the subject of intensive research due to their valuable pharmaceutical effects and contribution to plant disease… Expand
Impact of Environmental Factors on Stilbene Biosynthesis
TLDR
The effects of ultraviolet radiation, visible light, ultrasonication, mechanical stress, salt stress, drought, temperature, ozone, and biotic stress are reviewed in the context of enhancing stilbene biosynthesis, both in planta and in plant cell and organ cultures. Expand
Orchestration of the stilbene synthase gene family and their regulators by subgroup 2 MYB genes
TLDR
DNA affinity purification sequencing results a novel and potentially powerful tool for the analysis of novel uncharacterised regulators, however, it has not yet been applied in fruit crops and results show that MYB15 seems to play a role in regulating other stilbenoid-related TFs such as WRKY03, and suggests they are potentially involved in other processes such as the circadian rhythm or the synthesis of biotin. Expand
Phytostilbenes as agrochemicals: biosynthesis, bioactivity, metabolic engineering and biotechnology.
TLDR
All the aspects regarding phytostilbenes will be covered including their chemistry and biochemistry, regulation of their biosynthesis, biological activities in plants, molecular engineering of stilbene pathways in plants and microbes as well as their biotechnological production by plant cell systems. Expand
A Synchronized Increase of Stilbenes and Flavonoids in Metabolically Engineered Vitis vinifera cv. Gamay Red Cell Culture.
TLDR
A combined metabolomic and transcriptomic analysis reveals that the increase in both phenylpropanoid groups is accompanied by an induction of many of the flavonoid biosynthetic genes and no change in the expression levels of stilbene synthase. Expand
A review of dietary stilbenes: sources and bioavailability
Stilbenes are a class of phenolic metabolites found in various edible plants, such as grapevine, berries and peanuts. Their bioactivitiy and their potential benefits for human health have been theExpand
Biosynthesis of resveratrol and piceatannol in engineered microbial strains: achievements and perspectives
TLDR
This review will mainly focus on recent progress in production of resveratrol and piceatannol, including the various strategies used for their production. Expand
Retrospect and prospects of plant metabolic engineering
TLDR
This article includes recent techniques developed and their use in manipulation of glyoxalase metabolism for multiple abiotic stress tolerance in plants and their importance in the generation of improved crop varieties. Expand
The comparative analysis of stilbene production in cell cultures of two East Asian grape species Vitis amurensis Rupr. and Vitis coignetiae Pulliat
TLDR
The expression analysis of the genes encoding transcription factors potentially involved in regulation of STS genes revealed the significant species-specific differences, suggesting the molecular basis underlying the observed differences in stilbene biosynthetic potential of V. amurensis and V. coignetiae. Expand
Ectopic expression of VpSTS29, a stilbene synthase gene from Vitis pseudoreticulata, indicates STS presence in cytosolic oil bodies
TLDR
It is demonstrated that VpSTS29 is present in cytosolic oil bodies and can be transported into the vacuole at particular plant-developmental stages and exciting new insights are provided into the subcellular localisation of STS in plant cells and information about stilbene synthesis and storage is provided. Expand
The effect of ultraviolet-C and precursor feeding on stilbene biosynthesis in spruce Picea jezoensis.
TLDR
A positive effect of UV-C radiation and phenolic precursors on the content of stilbenes in spruce needles is revealed. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 214 REFERENCES
Metabolism and roles of stilbenes in plants
Abstract Stilbenes are a small family of plant secondary metabolites derived from the phenylpropanoid pathway, and produced in a number of unrelated plant species. These compounds have numerousExpand
Biosynthesis, metabolism, molecular engineering, and biological functions of stilbene phytoalexins in plants
TLDR
The biological significance of stilbenes in plants together with their biosynthesis pathway and their metabolism both by fungi and in planta is reviewed. Expand
Biosynthesis of plant-specific stilbene polyketides in metabolically engineered Escherichia coli
TLDR
Phenylpropionic acids, such as 4-coumaric acid and caffeic acid, can be efficiently converted to stilbene compounds by recombinant E. coli cells expressing plant biosynthetic genes and optimization of precursor conversion and cyclization of the bulky ferulic acid precursor by host metabolic engineering and protein engineering may afford the synthesis of even more structurally diverse stilBene compounds. Expand
Stilbene accumulation and expression of stilbene biosynthesis pathway genes in wild grapevine Vitis amurensis Rupr.
TLDR
An analysis of stilbenes spectrum, stilbene content, and expression of stILbene biosynthesis genes both in natural conditions and after ultraviolet (UV-C) elicitation in the leaves, petioles, berry skins, and seeds of wild-growing Vitis amurensis, a highly stress-tolerant plant species. Expand
Nature's assembly line: biosynthesis of simple phenylpropanoids and polyketides.
  • O. Yu, J. Jez
  • Biology, Medicine
  • The Plant journal : for cell and molecular biology
  • 2008
TLDR
This review focuses on four sub-groups of these polyphenolic compounds - polyketides, stilbenes, isoflavones and catechins and discusses the biosynthesis of these molecules, their physiological role in plants, and their striking pharmacological and physiological effects on humans. Expand
Regulation of Resveratrol Production in Vitis amurensis Cell Cultures by Calcium-Dependent Protein Kinases
TLDR
Investigation of the effects of overexpression of other members of the CDPK multigene family on resveratrol accumulation and growth parameters of grape cell cultures indicates that the VaCPK9,VaCPK13, and VaCPk21 genes are not involved in the regulation of stilbene biosynthesis in grape cells, while the Va CPK29 and VaCK20 genes are implicated in resver atrol biosynthesis as positive regulators. Expand
Phytoalexins in defense against pathogens.
TLDR
This review focuses on the biosynthesis and regulation of camalexin, and its role in plant defense, and details some of the phytoalexins produced by a range of crop plants from Brassicaceae, Fabaceae, Solanaceae, Vitaceae and Poaceae. Expand
Multi-level engineering facilitates the production of phenylpropanoid compounds in tomato
TLDR
It is shown that AtMYB12 not only increases the demand of flavonoid biosynthesis but also increases the supply of carbon from primary metabolism, energy and reducing power, which may fuel the shikimate and phenylalanine biosynthetic pathways to supply more aromatic amino acids for secondary metabolism. Expand
Structural, Functional, and Evolutionary Analysis of the Unusually Large Stilbene Synthase Gene Family in Grapevine1[W]
TLDR
Investigation of the high number of STS genes in grapevine finds a few sites under different selection pressures in CHS and STS sequences, whose potential functional consequences are discussed using a structural model of a typical STS from grapevine that is developed. Expand
MYB Transcription Factors as Regulators of Phenylpropanoid Metabolism in Plants.
TLDR
This review summarizes the current understanding of V-myb myeloblastosis viral oncogene homolog (MYB) proteins and their roles in the regulation of phenylpropanoid metabolism in plants. Expand
...
1
2
3
4
5
...