Regulation of spreading and growth of colon cancer cells by hepatocyte growth factor

@article{Jiang1993RegulationOS,
  title={Regulation of spreading and growth of colon cancer cells by hepatocyte growth factor},
  author={Wen Jiang and D. Lloyds and Malcom C. A. Puntis and Toshikazu Nakamura and Maurice B. Hallett},
  journal={Clinical & Experimental Metastasis},
  year={1993},
  volume={11},
  pages={235-242}
}
Hepatocyte growth factor (HGF), also known as scatter factor, regulates both cell motility and the growth of some cell types. We have determined the effects of HGF on the motility and growth of human colon cancer cell lines (HT115, HT29, HRT18 and HT55). Cell motility, as measured by dissociation from carrier beads or by scattering of cell colonies, was greatly increased in all cell lines. The effects were completely blocked by anti-HGF antibody. In contrast, cell growth of HT115, HT29 and… CONTINUE READING

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