Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member

@article{Mcpherron1997RegulationOS,
  title={Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member},
  author={Alexandra C. Mcpherron and Ann M. Lawler and Se-Jin Lee},
  journal={nature},
  year={1997},
  volume={387},
  pages={83-90}
}
The transforming growth factor-β (TGF-β) superfamily encompasses a large group of growth and differentiation factors playing important roles in regulating embryonic development and in maintaining tissue homeostasis in adult animals1. Using degenerate polymerase chain reaction, we have identified a new murine TGF-β family member, growth/differentiation factor-8 (GDF-8), which is expressed specifically in developing and adult skeletal muscle. During early stages of embryogenesis, GDF-8 expression… Expand
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