Regulation of simian virus 40 transcription: sensitive analysis of the RNA species present early in infections by virus or viral DNA.

@article{Parker1979RegulationOS,
  title={Regulation of simian virus 40 transcription: sensitive analysis of the RNA species present early in infections by virus or viral DNA.},
  author={Barbara A Parker and George R Stark},
  journal={Journal of virology},
  year={1979},
  volume={31 2},
  pages={360-9}
}
We have examined the discrete species of simian virus 40 (SV40) RNA present very early in infection of monkey cells with wild-type virus, with mutant tsA58 virus, and with the corresponding DNAs to distinguish between two classes of models for control of late transcription: (i) positive control mediated by large-T antigen and (ii) negative control mediated by a repressor protein associated with viral DNA in the virion. Total cytoplasmic or nuclear polyadenylated RNAs from infected cells were… CONTINUE READING
71 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 71 extracted citations

Similar Papers

Loading similar papers…