Regulation of self-renewal and differentiation by the intestinal stem cell niche

Abstract

The gastrointestinal epithelium is a highly organised tissue that is constantly being renewed. In order to maintain homeostasis, the balance between intestinal stem cell (ISC) self-renewal and differentiation must be carefully regulated. In this review, we describe how the intestinal stem cell niche provides a unique environment to regulate self-renewal and… (More)
DOI: 10.1007/s00018-011-0687-5

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Cite this paper

@article{Yeung2011RegulationOS, title={Regulation of self-renewal and differentiation by the intestinal stem cell niche}, author={Trevor M. Yeung and Luis A. Chia and Cynthia M. Kosinski and Calvin J. Kuo}, journal={Cellular and Molecular Life Sciences}, year={2011}, volume={68}, pages={2513-2523} }