Regulation of runt transcription by Drosophila segmentation genes.

  title={Regulation of runt transcription by Drosophila segmentation genes.},
  author={Martin Klingler and J Peter Gergen},
  journal={Mechanisms of development},
  volume={43 1},
The runt gene plays an important role in the genetic hierarchy that generates the segmented body pattern during the early stages of Drosophila embryogenesis. We studied mRNA expression in mutant embryos in order to investigate the regulation of runt transcription during these stages. We used sensitive whole-mount in situ hybridization procedures to identify the earliest, and therefore most likely direct regulatory effects. There are several distinct phases of runt expression in the early embryo… CONTINUE READING
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