Regulation of receptor protein-tyrosine phosphatase dimerization.

@article{Wijk2005RegulationOR,
  title={Regulation of receptor protein-tyrosine phosphatase dimerization.},
  author={Thea van der Wijk and Christophe Blanchetot and Jeroen den Hertog},
  journal={Methods},
  year={2005},
  volume={35 1},
  pages={73-9}
}
Receptor protein-tyrosine phosphatases (RPTPs) are single membrane spanning proteins belonging to the family of PTPs that, together with the antagonistically acting protein-tyrosine kinases (PTKs), regulate the protein phosphotyrosine levels in cells. Protein-tyrosine phosphorylation is an important post-translational modification that has a major role in cell signaling by affecting protein-protein interactions and enzymatic activities. Increasing evidence indicates that RPTPs, like RPTKs, are… CONTINUE READING

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