Regulation of radial glial motility by visual experience.

  title={Regulation of radial glial motility by visual experience.},
  author={Marc Tremblay and Vincent Fug{\`e}re and Jennifer J Tsui and Anne Schohl and Aydin Tavakoli and Bruno A. N. Travençolo and Luciano da Fontoura Costa and Edward S. Ruthazer},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={29 45},
Radial glia in the developing optic tectum express the key guidance molecules responsible for topographic targeting of retinal axons. However, the extent to which the radial glia are themselves influenced by retinal inputs and visual experience remains unknown. Using multiphoton live imaging of radial glia in the optic tectum of intact Xenopus laevis tadpoles in conjunction with manipulations of neural activity and sensory stimuli, radial glia were observed to exhibit spontaneous calcium… CONTINUE READING


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