Regulation of rabbit myometrial alpha adrenergic receptors by estrogen and progesterone.

  title={Regulation of rabbit myometrial alpha adrenergic receptors by estrogen and progesterone.},
  author={Lewis T. Williams and Robert J. Lefkowitz},
  journal={The Journal of clinical investigation},
  volume={60 4},
The effects of estrogen and progesterone on uterine alpha-adrenergic receptors were investigated by direct receptor-binding studies. Immature female rabbits were primed with estrogen by intramuscular injections for 4 days. Other rabbits were primed with progesterone by injections of estrogen for 4 days followed by injections of progesterone for 4 days. The alpha adrenergic antagonist, [3H]dihydroergocryptine, was used to directly assess the number and affinity of alpha adrenergic receptors in… 

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