Regulation of pyruvate oxidation in isolated rabbit heart mitochondria.
- Published 1972 in The Journal of biological chemistry
Abstract
Evidence is presented in support of the hypothesis that the pyruvate dehydrogenase multienzyme complex of intact rabbit heart mitochondria may be regulated by a phosphorylation-dephosphorylation mechanism. Mitochondria incubated in the presence of pyruvate plus L-malate and either ADP or uncoupler exhibit nearly identical, rapid rates of pyruvate oxidation… (More)
