Regulation of pyruvate dehydrogenase during infusion of fatty acids of varying chain lengths in the perfused rat heart.

Abstract

The effects of a homologous series of fatty acids with a chain length of two to eight on the rate of pyruvate oxidation and covalent interconversions of the pyruvate dehydrogenase complex (PDH) were studied in isolated perfused rat hearts. In the Langendorff-perfused heart beating at 5 Hz against an aortic pressure of 59 mmHg (7.85 kPa), a positive linear… (More)

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@article{Latip1985RegulationOP, title={Regulation of pyruvate dehydrogenase during infusion of fatty acids of varying chain lengths in the perfused rat heart.}, author={P M Latip{\"a}{\"a} and Keijo J. Peuhkurinen and Jussi Hiltunen and Ilmo E. Hassinen}, journal={Journal of molecular and cellular cardiology}, year={1985}, volume={17 12}, pages={1161-71} }