Regulation of prothymosin α by estrogen receptor α: molecular mechanisms and relevance in estrogen-mediated breast cell growth


Prothymosin α (PTα) is a small highly acidic protein found in the nuclei of virtually all mammalian tissues. Its high conservation in mammals and wide tissue distribution suggest an essential biological role. While the exact mechanism of action of PTα remains elusive, the one constant has been its relationship with the proliferative state of the cell and… (More)
DOI: 10.1038/sj.onc.1205995


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