Regulation of proteasome-mediated protein degradation during oxidative stress and aging.

Abstract

Protein degradation is a physiological process required to maintain cellular functions. There are distinct proteolytic systems for different physiological tasks under changing environmental and pathophysiological conditions. The proteasome is responsible for the removal of oxidatively damaged proteins in the cytosol and nucleus. It has been demonstrated… (More)
DOI: 10.1515/BC.2008.029

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