Regulation of proenkephalin gene expression by angiotensin in bovine adrenal medullary cells: Molecular mechanisms and nature of the second messenger systems

@article{Stachowiak1991RegulationOP,
  title={Regulation of proenkephalin gene expression by angiotensin in bovine adrenal medullary cells: Molecular mechanisms and nature of the second messenger systems},
  author={Michal K. Stachowiak and Alan M. Poisner and H K Jiang and P Hudson and J. -S. Hong},
  journal={Molecular and Cellular Neuroscience},
  year={1991},
  volume={2},
  pages={213-220}
}
Expression of the Proenkephalin A Gene and [Met5]‐Enkephalin Secretion Induced by Arachidonic Acid in Bovine Adrenal Medullary Chromaffin Cells: Involvement of Second Messengers
TLDR
The results suggest that the Ca2+/calmodulin pathway, but not the protein kinase A or PKC pathway, is partially involved in mediating the AA‐induced increases of the long‐term secretion of ME and the levels of proENK mRNA.
Effects of [Sar1] Angiotensin II on Proenkephalin Gene Expression and Secretion of [Met5]Enkephalin in Bovine Adrenal Medullary Chromaffin Cells
TLDR
The results suggest that All in BAMC cells exerts a major effect on the long‐term regulation of expression of proENK mRNA and secretion of ME, which appear to be mediated by type 1‐like All receptors.
Transcription of (pro)renin mRNA in the rat adrenal cortex, and the effects of ACTH treatment and a low sodium diet.
TLDR
It is suggested that angiotensin II, as well as being the major regulator of the glomerulosa, may also have some role in inner adrenocortical zone functions.
From Angiotensin to Renin to Prorenin and from the Adrenal to the Kidney to the Placenta and the Lungs: An Historical Journey
  • A. Poisner
  • Biology, Medicine
    Selected Chapters from the Renin-Angiotensin System
  • 2020
TLDR
This chapter reviews what my colleagues and I have learned from over a half-century of studying the renin-angiotensin system (RAS) in a wide variety of biological preparations, while awareness of its complexity has exploded.

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The experiments suggest that PMA increases protein kinase activity and secretion in chromaffin cells and raise the possibility thatprotein kinase C modulates catecholamine secretion in Chromaffin Cells.
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