Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells.

@article{Eisenreich2013RegulationOP,
  title={Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells.},
  author={Andreas Eisenreich and Andreas Zakrzewicz and Kilian Huber and Hannes Thierbach and Wojciech Pepke and Petra Goldin-Lang and Heinz-Peter Schultheiss and Axel Radlach Pries and Ursula Rauch},
  journal={Oncology reports},
  year={2013},
  volume={30 1},
  pages={462-70}
}
Alternative splicing is a key regulatory mechanism for cellular metabolism controlling cell proliferation and angiogenesis, both of which are crucial processes for tumorigenesis under hypoxia. Human cells express two tissue factor (TF) isoforms, alternatively spliced TF (asTF) and 'full length' TF (flTF). flTF is the major source of thrombogenicity whereas, the function of soluble asTF, particularly in cancer, is widely unknown. In the present study, we examined the impact of alternative… CONTINUE READING
Highly Cited
This paper has 36 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Tissue factor in tumor microenvironment: a systematic review

Journal of hematology & oncology • 2014
View 6 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 39 references

A study of the suppressive effect on human pancreatic adenocarcinoma cell proliferation and angiogenesis by stable plasmid - based siRNA silencing of cSrc gene expression

H Zhao
Oncol Rep • 2012

CCN 1 : CCN 1 : a novel inflammation - regulated biphasic immune cell migration modulator

M Löbel, S Bauer, C Meisel
Cell Mol Life Sci • 2012

Similar Papers

Loading similar papers…