Regulation of pancreatic islet gene expression in mouse islets by pregnancy.

Abstract

Pancreatic β cells adapt to pregnancy-induced insulin resistance by unclear mechanisms. This study sought to identify genes involved in β cell adaptation during pregnancy. To examine changes in global RNA expression during pregnancy, murine islets were isolated at a time point of increased β cell proliferation (E13.5), and RNA levels were determined by two… (More)
DOI: 10.1677/JOE-10-0298

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