Regulation of ovine fetal pituitary function by corticotrophin-releasing hormone, arginine vasopressin and cortisol in vitro.

@article{L1994RegulationOO,
  title={Regulation of ovine fetal pituitary function by corticotrophin-releasing hormone, arginine vasopressin and cortisol in vitro.},
  author={Fu-qu L{\"u} and Kaiping Yang and John R. G. Challis},
  journal={The Journal of endocrinology},
  year={1994},
  volume={143 1},
  pages={199-208}
}
Parturition and fetal organ maturation in sheep are associated with increased activity of the fetal hypothalamic-pituitary-adrenal (HPA) axis during late pregnancy. However, the factors responsible for HPA activation remain unclear. In the fetal pituitary, levels of pro-opiomelanocortin (POMC) mRNA increase, but the numbers of binding sites for… CONTINUE READING