Regulation of organic osmolyte concentrations in tubules from rat renal inner medulla.

@article{Wirthensohn1989RegulationOO,
  title={Regulation of organic osmolyte concentrations in tubules from rat renal inner medulla.},
  author={Gabriele Wirthensohn and S Lefrank and Michael Schmolke and Walter G. Guder},
  journal={The American journal of physiology},
  year={1989},
  volume={256 1 Pt 2},
  pages={F128-35}
}
Glycerophosphorylcholine, inositol, and sorbitol were measured in rat kidney homogenates and tubules from inner medulla and papilla by enzymatic spectrophotometric techniques. Organic osmolytes exhibited their highest concentrations in the papillary tip. In contrast to glycerophosphorylcholine and sorbitol, inositol was of similar high concentrations in inner and outer medulla. Freshly prepared inner medullary tubules maintained tissue osmolyte concentrations under control, antidiuretic, and… CONTINUE READING

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