Regulation of orexin neurons by the monoaminergic and cholinergic systems.

  title={Regulation of orexin neurons by the monoaminergic and cholinergic systems.},
  author={Akihiro Yamanaka and Yo Muraki and Natsuko Tsujino and Katsutoshi Goto and Takeshi Sakurai},
  journal={Biochemical and biophysical research communications},
  volume={303 1},
Orexins are a pair of neuropeptides implicated in energy homeostasis and arousal. Here we characterize the electrophysiological properties of orexin neurons using slice preparations from transgenic mice in which orexin neurons specifically express green fluorescent protein. Orexin neurons showed high frequency firing with little adaptation by injecting a positive current. The hyperpolarization-activated current was observed in orexin neurons by a negative current injection. The… CONTINUE READING

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