Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157


Neuronal health is essential for the long-term integrity of the brain. In this study, we characterized the novel E3 ubiquitin ligase ring finger protein 157 (RNF157), which displays a brain-dominant expression in mouse. RNF157 is a homolog of the E3 ligase mahogunin ring finger-1, which has been previously implicated in spongiform neurodegeneration. We… (More)
DOI: 10.1038/cdd.2014.163


8 Figures and Tables