Regulation of neuronal nicotinic receptor traffic and expression

  title={Regulation of neuronal nicotinic receptor traffic and expression},
  author={Annalisa Gaimarri and Milena Moretti and Loredana Riganti and A. M. T. Zanardi and Cecilia Gotti},
  journal={Brain Research Reviews},
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of cation channels widely distributed in the brain, whose subunit composition and biophysical properties vary depending on the subtype and the area of the brain in which they are found. Brain nAChRs are also the target of nicotine, the most widespread drug of abuse. Chronic nicotine exposure differentially affects the number, subunit composition, stoichiometry and functional state of some nAChR subtypes, leaving others… CONTINUE READING

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