Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene.

@article{Mee2004RegulationON,
  title={Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene.},
  author={Christopher J. Mee and Edward C G Pym and Kevin Moffat and Richard A. Baines},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2004},
  volume={24 40},
  pages={8695-703}
}
Dynamic changes in synaptic connectivity and strength, which occur during both embryonic development and learning, have the tendency to destabilize neural circuits. To overcome this, neurons have developed a diversity of homeostatic mechanisms to maintain firing within physiologically defined limits. In this study, we show that activity-dependent control of… CONTINUE READING