Regulation of neural markers nestin and GFAP expression by cultivated bone marrow stromal cells

  title={Regulation of neural markers nestin and GFAP expression by cultivated bone marrow stromal cells},
  author={Sabine Wislet-Gendebien and Pierre Leprince and Gustave Moonen and Bernard Rogister},
  journal={Journal of Cell Science},
  pages={3295 - 3302}
Bone marrow stromal cells can differentiate into many types of mesenchymal cells, i.e. osteocyte, chondrocyte and adipocyte, but can also differentiate into non-mesenchymal cells, i.e. neural cells under appropriate in vivo experimental conditions (Kopen et al., 1999; Brazelton et al., 2000; Mezey et al., 2000). This neural phenotypic plasticity allows us to consider the utilization of mesenchymal stem cells as cellular material in regenerative medicine. In this study, we demonstrate that… 

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