Regulation of net hepatic glucose uptake in vivo.

  title={Regulation of net hepatic glucose uptake in vivo.},
  author={Michael J. Pagliassotti and Alan D. Cherrington},
  journal={Annual review of physiology},
Increases in the glucose level in the absence of the portal signal or changes in insulin elicits little if any glucose uptake by the liver. NHGU is augmented by a rise in insulin (or drop in glucagon) and is further stimulated by the presence of a portal signal. Under postprandial conditions, NHGU will depend on the dynamic interaction between the pancreatic hormones, glucose and the portal signal. Moreover, in a simulated postprandial environment, the quantitative impact of the portal signal… CONTINUE READING

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