Regulation of nerve growth factor content in C6 glioma cells by β-adrenergic receptor stimulation

@article{Schwartz1977RegulationON,
  title={Regulation of nerve growth factor content in C6 glioma cells by β-adrenergic receptor stimulation},
  author={Joan P. Schwartz and Erminio Costa},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1977},
  volume={300},
  pages={123-129}
}
The C6 glioma cell line contains nerve growth factor (NGF) which can be released into the medium. Treatment of the cells with beta-adrenoceptor agonists resulted in increased content of NGF in both the cells and the medium within a few hours, whereas alpha-adrenoceptor agonists were ineffective. The response was blocked by beta- but not alpha-adrenoceptor… CONTINUE READING