Regulation of natural genetic transformation and acquisition of transforming DNA in Streptococcus pneumoniae.

@article{Johnsborg2009RegulationON,
  title={Regulation of natural genetic transformation and acquisition of transforming DNA in Streptococcus pneumoniae.},
  author={Ola Johnsborg and Leiv Sigve H{\aa}varstein},
  journal={FEMS microbiology reviews},
  year={2009},
  volume={33 3},
  pages={
          627-42
        }
}
The ability of pneumococci to take up naked DNA from the environment and permanently incorporate the DNA into their genome by recombination has been exploited as a valuable research tool for 80 years. From being viewed as a marginal phenomenon, it has become increasingly clear that horizontal gene transfer by natural transformation is a powerful mechanism for generating genetic diversity, and that it has the potential to cause severe problems for future treatment of pneumococcal disease. This… CONTINUE READING

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