Regulation of natriuretic peptide secretion by the heart.

@article{Thibault1999RegulationON,
  title={Regulation of natriuretic peptide secretion by the heart.},
  author={Ga{\'e}tan Thibault and Farhad Abbassi Amiri and Ra{\'u}l Ignacio Ramos Garc{\'i}a},
  journal={Annual review of physiology},
  year={1999},
  volume={61},
  pages={193-217}
}
Secreted by the heart, more specifically by atrial cardiomyocytes under normal conditions but also by ventricular myocytes during cardiac hypertrophy, natriuretic peptides are now considered important hormones in the control of blood pressure and salt and water excretion. Studies on natriuretic peptide secretagogues and their mechanisms of action have been complicated by hemodynamic changes and contractions to which the atria are constantly subjected. It now appears that atrial stretch through… CONTINUE READING

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