Regulation of myeloid and lymphoid development of hematopoietic stem cells by bone marrow stromal cells.

Abstract

Development of hematopoietic stem cells is regulated by stromal cells of the bone marrow. Many stromal cell lines have been established from temperature-sensitive SV40 large T-antigen gene transgenic mice and used to examine regulation of the purified stem cells. When the sorted stem cells were cocultured on the stromal cell layers, cobblestone formation… (More)

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@article{Obinata1998RegulationOM, title={Regulation of myeloid and lymphoid development of hematopoietic stem cells by bone marrow stromal cells.}, author={Masuo Obinata and Rin Okuyama and Koichi Matsuda and Masato Koguma and Nobuhiro Yanai}, journal={Leukemia & lymphoma}, year={1998}, volume={29 1-2}, pages={61-9} }