Regulation of murine embryonic epithelial cell differentiation by transforming growth factors beta.

@article{Gehris1992RegulationOM,
  title={Regulation of murine embryonic epithelial cell differentiation by transforming growth factors beta.},
  author={Amy L. Gehris and Robert Michael Greene},
  journal={Differentiation; research in biological diversity},
  year={1992},
  volume={49 3},
  pages={
          167-73
        }
}
The expression of some members of the transforming growth factor beta (TGF beta) family of genes in embryonic craniofacial tissue suggests a functional role for these molecules in orofacial development. In an attempt to ascertain a role for the TGF beta s during palatal ontogeny, murine palatal shelves were excised on gestation day (GD) 12, prior to overt epithelial differentiation, grown in organ culture under serum-free conditions and exposed to TGF beta 1 and TGF beta 2 for 18 or 42 h… CONTINUE READING
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