Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance

@inproceedings{Kim2010RegulationOM,
  title={Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance},
  author={S Kim and Ji-young Kim and Nak-Won Choe and Ick-Hyun Cho and Ju-Ryoung Kim and Dong-wook Kim and Jin-Ee Seol and Song Eun Lee and Hoon Kook and Kwang-Il Nam and Hyun Kook and Young-Yil Bhak and Sang-Beom Seo},
  booktitle={Nucleic acids research},
  year={2010}
}
The dynamic exchange of histone lysine methylation status by histone methyltransferases and demethylases has been previously implicated as an important factor in chromatin structure and transcriptional regulation. Using immunoaffinity TAP analysis, we purified the WHISTLE-interacting protein complexes, which include the heat shock protein HSP90α and the jumonji C-domain harboring the histone demethylase JMJD1C. In this study, we demonstrate that JMJD1C specifically demethylates histone H3K9… CONTINUE READING

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