Regulation of monocyte/macrophage polarisation by extracellular RNA.

Abstract

Monocytes/macrophages respond to external stimuli with rapid changes in the expression of numerous inflammation-related genes to undergo polarisation towards the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype. We have previously shown that, independently of Toll-like receptor activation, extracellular RNA (eRNA) could exert pro-thrombotic and pro… (More)
DOI: 10.1160/TH14-06-0507

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